Neurogenic pulmonary edema (NPE) is a relatively rare form of pulmonary edema caused by an increase in pulmonary interstitial and alveolar fluid. Material and methods: The case of a 66-year-old male patient with NPE caused by repeated epileptic seizures is reported. Neurogenic pulmonary edema (NPE) is a non‐cardiogenic pulmonary edema that is caused by an acute central nervous system injury and usually develops rapidly after an injury. • Signs of NPE in computed tomography (CT) examinations were retrospectively assessed in patients admitted for acute seizures. The diagnosis 'tonic clonic seizure' is frequently established by emergency physicians on scene. Although several episodes of NPE resolve spontaneously, the condition may … Neurogenic pulmonary edema develops within a few hours after a neurologic insult, and diagnosis requires exclusion of other causes of pulmonary edema (eg, high-altitude pulmonary edema). The mechanism of neurogenic pulmonary edema in epilepsy ... sive seizure-related outpouring of central sympathetic activity, which leads to an increase in pulmonary vascular resistance [13, 14]. ... seizures, and 1% occurred after cerebral trauma. Intracranial hypertension elic- Neurogenic pulmonary edema (NPE) is an underdiagnosed clinical entity. Neurogenic pulmonary edema may be a complication of the terminal phase of cerebral tumors. We report two cases of NPE and review the literature on NPE cases reported since 1990. Neurogenic pulmonary edema (NPE) may be involved in seizure-related complications and SUDEP. The aim of this study is to explore the exact mechanism of epilepsy-induced NPE. Epileptic seizures — Among all patients with epilepsy the occurrence of NPE is rare. Rapid resolution of pulmonary oedema is well documented by X-ray and computed tomography images. Neurogenic pulmonary oedema as a rare complication of epileptic seizures Abstract Introduction: Neurogenic pulmonary oedema (NPE) is a very rare complication of epileptic seizures, which could potentially increase mortality. We report a case of acute pulmonary oedema after a tonic clonic seizure. • NPE was detected in 5 out of 47 patients • In patients with epilepsy mortality due to accidents, asphyxia, cardiac arrhythmias or postictal neurogenic pulmonary oedema (NPO) is twice as high as in the general population. The diagnosis of neurogenic pulmonary edema is based on the occurrence of edema after a neurologic event/insult and the exclusion of other plausible causes. Introduction: Neurogenic pulmonary oedema (NPE) is a very rare complication of epileptic seizures, which could potentially increase mortality. drostatic pressure in the development of neurogenic pulmonary edema. NPE has been documented in patients with cere-bral hemorrhage, subarachnoid hemorrhage, cerebral thrombosis, acute open and closed Commonly seen after significant neurological trauma, NPE has also been described after seizure. A 21-year-old man had a seizure episode following cranioplasty. Neurogenic pulmonary edema is an etiological subtype of non-cardiogenic pulmonary edema, classified as a subtype of the acute respiratory distress syndrome by the Berlin definition.. Acute pulmonary edema following significant injury to the central nervous system is known as neurogenic pulmonary edema (NPE). Its pathophysiology is multifactorial but largely unknown. Reported etiologies of neurogenic pulmonary edema are listed in the table . While many pathogenic theories have been proposed, the exact mechanism remains unclear. 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